Exit 5
US 17 / US 321 – Hardeeville, Estill, SavannahHardeeville, SC
28
Exit 8
US 278 – Beaufort, Hilton Head Island, Bluffton, Parris IslandHardeeville, SC
17
Exit 18
Bees Creek Road – SwitzerlandJasper, SC
0
Exit 21
SC 336 – RidgelandRidgeland, SC
11
Exit 22
US 17 south – RidgelandRidgeland, SC
2
Exit 28
SC 462 – CoosawhatchieJasper, SC
Exit 33
US 17 north – Charleston, Beaufort, Port RoyalPoint South, SC
14
Exit 38
SC 68 – Yemassee, Hampton, VarnvilleYemassee, SC
15
Exit 42
US 21 – Yemassee, OrangeburgColleton, SC
Exit 53
SC 63 to US 17 Alt. – WalterboroWalterboro, SC
6
Exit 57
SC 64 – Walterboro, LodgeWalterboro, SC
89
Exit 62
Road 34Colleton, SC
Exit 68
SC 61 – Canadys, BranchvilleColleton, SC
1
Exit 77
US 78 – St. George, BranchvilleSt. George, SC
Exit 82
US 178 – Harleyville, BowmanDorchester, SC
Exit 86A
I-26 – Charleston, ColumbiaOrangeburg, SC
Exit 86B
I-26 West – Charleston, ColumbiaOrangeburg, SC
Exit 90
US 176 – Holly Hill, CameronOrangeburg, SC
Exit 93
US 15 – Holly HillOrangeburg, SC
Exit 97
US 15 south / US 301 south – OrangeburgOrangeburg, SC
Exit 98
SC 6 – Eutawville, Santee, ElloreeSantee, SC
74
Exit 102
US 15 north / US 301 north / Road 400 – North SanteeClarendon, SC
8
Exit 108
Road 102 – SummertonSummerton, SC
13
Exit 115
US 301 – Manning, SummertonClarendon, SC
Exit 119
SC 261 (Paxville Highway) – Manning, PaxvilleClarendon, SC
160
Exit 122
US 521 – Sumter, Manning, AlcoluClarendon, SC
16
Exit 132
SC 527 – Sardinia, Bishopville, KingstreeClarendon, SC
Exit 135
US 378 – Turbeville, Sumter, Lake CitySumter, SC
Exit 141
SC 53 / SC 58 – ShilohSumter, SC
Exit 146
SC 341 – Lake City, Lynchburg, OlantaSumter, SC
Exit 150
SC 403 – Sardis, TimmonsvilleFlorence, SC
Exit 153
Honda Way – TimmonsvilleFlorence, SC
Exit 157
US 76 (West Palmetto Street) – Florence, TimmonsvilleFlorence, SC
Exit 160A
I-20 west / I-20 Bus. east (David McLeod Boulevard) – Florence, ColumbiaFlorence, SC
19
Exit 160B
143
Exit 164
US 52 (Lucas Street) – Florence, DarlingtonFlorence, SC
63
Exit 169
TV Road – Quinby, FlorenceFlorence, SC
Exit 170
SC 327 – Florence, Marion, Myrtle BeachFlorence, SC
Exit 181A
SC 38 – Latta, Marion, BennettsvilleDillon, SC
Exit 181B
Exit 190
SC 34 – DillonDillon, SC
Exit 193
SC 9 / SC 57 – Dillon, Little Rock, BennettsvilleDillon, SC
Exit NC1
US 301 / US 501 – Rowland, Laurinburg, DillonDillon, SC
Alpha Release News: see notes.